{"page":"\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-c03aa079.css\" /\u003e\n\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-517835be.css\" media=\"all\" /\u003e\n\u003cdiv data-title='Merck recalls blockbuster arthritis drug' data-url='/boclips/videos/5c54c332d8eafeecae15f76e' data-video-url='/boclips/videos/5c54c332d8eafeecae15f76e' id='bo_player_modal'\u003e\n\u003cdiv class='boclips-resource-page modal-dialog panel-container'\u003e\n\u003cdiv class='react-notifications-root'\u003e\u003c/div\u003e\n\u003cdiv class='rp-header'\u003e\n\u003cdiv class='rp-type'\u003e\n\u003ci aria-hidden='true' class='fai fa-regular fa-circle-play'\u003e\u003c/i\u003e\nVideo\n\u003c/div\u003e\n\u003ch1 class='rp-title' id='video-title'\u003e\nMerck recalls blockbuster arthritis drug\n\u003c/h1\u003e\n\u003cdiv class='rp-actions'\u003e\n\u003cdiv class='mr-1'\u003e\n\u003ca class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"\u003e\u003cspan\u003e\u003cspan\u003eGet Free Access\u003c/span\u003e\u003cspan class=\"\"\u003e for 10 Days\u003c/span\u003e\u003cspan\u003e!\u003c/span\u003e\u003c/span\u003e\u003c/a\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-body'\u003e\n\u003cdiv class='rp-info'\u003e\n\u003cdiv aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'\u003e\u0026times;\u003c/div\u003e\n\u003ci aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003ci aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003cdiv class='rp-rating'\u003e\n\u003cspan class='resource-pool'\u003e\n\u003cspan class='pool-label'\u003ePublisher:\u003c/span\u003e\n\u003cspan class='pool-name'\u003e\n\u003cspan class='text'\u003e\u003ca data-publisher-id=\"30356011\" href=\"/search?publisher_ids%5B%5D=30356011\"\u003eCurated Video\u003c/a\u003e\u003c/span\u003e\n\u003c/span\u003e\n\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-description'\u003e\n\u003cspan class='short-description'\u003eNew York, New York, 30 September 20041. Wide of Merck news conference2. Cutaway of media3. Cutaway camera person4. SOUNDBITE: (English) Raymond V. Gilmartin, Chairman, President and Chief Executive Officer, Merck and Company, Inc.:\"We...\u003c/span\u003e\n\u003cspan class='full-description hide'\u003eNew York, New York, 30 September 2004\u003cbr/\u003e1. Wide of Merck news conference\u003cbr/\u003e2. Cutaway of media\u003cbr/\u003e3. Cutaway camera person\u003cbr/\u003e4. SOUNDBITE: (English) Raymond V. Gilmartin, Chairman, President and Chief Executive Officer, Merck and Company, Inc.:\u003cbr/\u003e\"We are voluntarily withdrawing Vioxx effective today. We are taking this action because we believe it best serves the interests of patients. We believe it  would have been possible to continue to market Vioxx with labelling that would incorporate these new data. However, given the availability of alternative therapies and the questions raised by the data, we concluded that a voluntary withdrawal is the responsible course to take.\"\u003cbr/\u003eFILE: Location unknown, Recent\u003cbr/\u003e5. Various of Vioxx drug being bottled\u003cbr/\u003eNew York, New York, 30 September 2004\u003cbr/\u003e6. SOUNDBITE: (English) Raymond V. Gilmartin, Chairman, President and Chief Executive Officer, Merck and Company, Inc.:\u003cbr/\u003e\"And as a result of this decision, the company currently expects earnings per share to be negatively affected by fifty to sixty cents.\"\u003cbr/\u003eFILE: Location unknown, Recent\u003cbr/\u003e7. Various of Vioxx drug being produced\u003cbr/\u003e8. Merck laboratories\u003cbr/\u003eNew York, New York, 30 September 2004\u003cbr/\u003e9. SOUNDBITE: (English) Robert Langreth, Senior Editor, Forbes Magazine:\u003cbr/\u003e\"Well this is an absolute disaster for Merck. It's one of their biggest products, 2.5 (b) billion dollars in sales, and that's all gone. This (Vioxx), when they introduced it in 1999 was going to be their primary growth driver for the future, and now it's gone, so that's an absolute disaster. One of the analysts I was talking to said that people were already reducing estimates for next year by 70 cents and he was saying that's just way, way too low. You're going to have reduce estimates enormously for next year. And, compounding the problem, Merck loses patent protection on its biggest selling drug, the cholesterol fighting drug Zocor 2006, and now it will be without Vioxx and it is going to be without Zocor soon. Another question to look at is the legal liability ramifications for Merck. This could be a huge, huge legal liability question. Every time a drug gets recalled, you see class action lawsuits. And here is a very popular drug used by millions and millions of people.\"\u003cbr/\u003eFILE: New Jersey, Recent\u003cbr/\u003e10. Exteriors of Merck research labs\u003cbr/\u003eFILE: New York, Recent\u003cbr/\u003e11. Pfizer (maker of Celebrex) world headquarters in New York City\u003cbr/\u003eUS pharmaceutical giant Merck \u0026amp; Co. has halted worldwide sales of its popular arthritis drug Vioxx, after new data from clinical trials found an increased risk of heart attack and stroke. \u003cbr/\u003eThe company's stock price plunged more than 26 percent as the company announced the recall will hurt its earnings.\u003cbr/\u003eMerck said on Thursday that data from the trial showed the increased risk of heart attack and other cardiovascular complications began 18 months after patients started taking Vioxx. \u003cbr/\u003eVioxx was once viewed as possibly being able to prevent some cancers.\u003cbr/\u003eMerck estimates that about 2 (m) million people worldwide are currently taking Vioxx and a total of 84 (m) million have taken it since it came on the market with great fanfare in 1999.\u003cbr/\u003eThe data comes from a three-year study aimed at showing that Vioxx at a 25 milligram dose prevents recurrence of polyps in the colon and rectum. Such polyps can turn cancerous. \u003cbr/\u003eThe trial was stopped after Merck discovered the higher heart risk compared to patients taking dummy pills.\u003cbr/\u003eMedical experts advised patients to stop taking Vioxx and consult their doctor about alternatives, but said patients should not panic because the risk of a heart attack was still relatively low.\u003cbr/\u003eVioxx is one of Merck's most important drug products, with 2.5 (b) billion US dollars in sales in 2003 - about 11 percent of the company's 22.49 (b) billion US dollars in revenue that year. \u003cbr/\u003eBut sales dipped 18 percent in the second quarter of this year to 653 (m) million US dollars, partly due to increasing concerns about the drug's safety.\u003cbr/\u003eMerck, the world's third-biggest drug maker, announced the news before the stock market opened. \u003cbr/\u003eIn morning trading on the New York Stock Exchange (NYSE), Merck shares plunged 11.98 US dollars, or more than 26 percent, to 33.09 US dollars.\u003cbr/\u003eMerck's announcement stands to benefit rival Pfizer Inc., the world's biggest drug maker. \u003cbr/\u003eThe two companies have been battling for market share with Pfizer's Celebrex dominating the market with about 5 (b) billion US dollars in US sales alone last year. \u003cbr/\u003ePfizer shares were up 68 cents, or more than 2 percent, in early trading on the NYSE.\u003cbr/\u003e\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='action-container flex justify-between'\u003e\n\u003cbutton aria-expanded='false' aria-label='Read more description' class='rp-full-description' type='button'\u003e\n\u003ci class='fai fa-solid fa-align-left'\u003e\u003c/i\u003e\n\u003cspan id='read_more'\u003eRead More\u003c/span\u003e\n\u003c/button\u003e\n\u003cdiv class='rp-report'\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv aria-labelledby='resource-details-heading' class='rp-info-section'\u003e\n\u003ch2 class='title' id='resource-details-heading'\u003eResource 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