{"page":"\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-c03aa079.css\" /\u003e\n\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-517835be.css\" media=\"all\" /\u003e\n\u003cdiv data-title='A car crash victim gets a rare transplant operation' data-url='/boclips/videos/5c54c197d8eafeecae15352d' data-video-url='/boclips/videos/5c54c197d8eafeecae15352d' id='bo_player_modal'\u003e\n\u003cdiv class='boclips-resource-page modal-dialog panel-container'\u003e\n\u003cdiv class='react-notifications-root'\u003e\u003c/div\u003e\n\u003cdiv class='rp-header'\u003e\n\u003cdiv class='rp-type'\u003e\n\u003ci aria-hidden='true' class='fai fa-regular fa-circle-play'\u003e\u003c/i\u003e\nVideo\n\u003c/div\u003e\n\u003ch1 class='rp-title' id='video-title'\u003e\nA car crash victim gets a rare transplant operation\n\u003c/h1\u003e\n\u003cdiv class='rp-actions'\u003e\n\u003cdiv class='mr-1'\u003e\n\u003ca class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"\u003e\u003cspan\u003e\u003cspan\u003eGet Free Access\u003c/span\u003e\u003cspan class=\"\"\u003e for 10 Days\u003c/span\u003e\u003cspan\u003e!\u003c/span\u003e\u003c/span\u003e\u003c/a\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-body'\u003e\n\u003cdiv class='rp-info'\u003e\n\u003cdiv aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'\u003e\u0026times;\u003c/div\u003e\n\u003ci aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003ci aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003cdiv class='rp-rating'\u003e\n\u003cspan class='resource-pool'\u003e\n\u003cspan class='pool-label'\u003ePublisher:\u003c/span\u003e\n\u003cspan class='pool-name'\u003e\n\u003cspan class='text'\u003e\u003ca data-publisher-id=\"30356011\" href=\"/search?publisher_ids%5B%5D=30356011\"\u003eCurated Video\u003c/a\u003e\u003c/span\u003e\n\u003c/span\u003e\n\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-description'\u003e\n\u003cspan class='short-description'\u003eAP Television is adhering to Iranian law that stipulates all media are banned from providing BBC Persian or VOA Persian any coverage from Iran, and under this law if any media violate this ban the Iranian authorities can immediately shut...\u003c/span\u003e\n\u003cspan class='full-description hide'\u003eAP Television is adhering to Iranian law that stipulates all media are banned from providing BBC Persian or VOA Persian any coverage from Iran, and under this law if any media violate this ban the Iranian authorities can immediately shut down that organisation in Tehran.\u003cbr/\u003eTehran, Iran, April 26, 2010\u003cbr/\u003e1. Mid pan from monitors showing inside of patient's trachea to doctor doing bronchoscopy checking for abnormalities \u003cbr/\u003e2. Close tilt-up from the bronchoscope to surgeon's face \u003cbr/\u003e3. Close-up patient's trachea pictures being printed on paper \u003cbr/\u003e4. Close-up of sign reading (English) \"Interventional Bronchoscopy \u0026amp; Laser Unit\" \u003cbr/\u003e5. Wide pan from one operating team inside theatre to another in the same room\u003cbr/\u003e6. SOUNDBITE (Farsi) Dr. Hamid Reza Jabbari, respiratory consultant, trachea transplant research team \u003cbr/\u003e\"We have tested this operation on one human case so far and it was impossible for this case to undergo any other treatment such as surgery. We fully carried out this operation on this patient and it was quite successful. The patient's respiratory rhythm and her breathing curve are completely normal and acceptable.\" \u003cbr/\u003e7. Mid of Dr. Jabbari in operating room \u003cbr/\u003e8. Close-up bronchoscopy video on monitor \u003cbr/\u003e9. Wide of operating room\u003cbr/\u003e10. Wide exterior of Masih Daneshvari hospital in northern Tehran \u003cbr/\u003e11. Close-up of hospital sign reading (Farsi) \"Tuberculosis and Lung Diseases Educative, Research and Treatment Centre \" \u003cbr/\u003e12. Wide of news conference releasing details about the trachea operation  \u003cbr/\u003e13. Close up of slides on screen showing various slides of human trachea \u003cbr/\u003e14. Mid of presser and the trachea transplant research team sitting on podium \u003cbr/\u003e15. Close up of screen showing a bronchoscopy operation \u003cbr/\u003e16. SOUNDBITE (Farsi) Ali Akbar Velayati, paediatric consultant \u0026amp; chief adviser to Iran 's Supreme Leader \u003cbr/\u003e\"(Nanocapsules and the polymeric matrix containing trachea tissue elements) are injected into the trachea. The material forms a new scaffold around the damaged trachea; then the stem cells that are constantly circulating in the blood reach the scaffold and start making cartilage and this produced cartilage is like it is reborn and completely new. This has been done for the first time in the world without any doubt.\" \u003cbr/\u003e17. Mid shot of Dr. Jalaladdin Ghanavi, head of bio-artificial trachea transplant research team in laboratory \u003cbr/\u003e18. Close-up of microscope \u003cbr/\u003e19. Mid shot of Dr. Ghanavi walking from microscope to bio safety cabinet \u003cbr/\u003e20. SOUNDBITE (Farsi) Dr. Jalaladdin Ghanavi, head of bio-artificial trachea transplant research team \u003cbr/\u003e\"Nowhere in the world, a complete functional organ (trachea), that has tissue and a double-structure (has both inner and outer parts of trachea) has been produced yet.\" \u003cbr/\u003e21. Zoom out of Ghanavi's hand holding a beaker with an artificial trachea scaffold inside \u003cbr/\u003e22. Close up tilt-down of artificial trachea in the beaker being held by doctor \u003cbr/\u003e23. Close up pull focus from microscope to doctor working in bio safety cabinet \u003cbr/\u003e24. Mid shot of doctor working in safety cabinet \u003cbr/\u003e25. Close up of trachea tissue being moved about in beaker with a syringe \u003cbr/\u003e26. Mid shot of  doctor and laboratory technician \u003cbr/\u003e27. SOUNDBITE: (Farsi), Dr. Jalaladdin Ghanavi, head of bio-artificial trachea transplant research team\u003cbr/\u003e\"(What motivated us to carry out this research) was first the large number of car crashes that leave many patients in coma with damaged tracheas and most of the time we have to place some pipes in the tightened parts of trachea. The second reason which was more common before was soldiers who had been chemically injured. When a chemical weapon is blown up near you, the first part of body which is harmed is your eyes. Then skin is damaged and also trachea is next as soon as the injured takes the first breath. We had an incredibly high number of such patients.\" \u003cbr/\u003e28. Mid of hospital's waiting room with patients of breathing system ailments \u003cbr/\u003eA young woman has become the first person in Iran to benefit from a windpipe transplant using a ground breaking technique where doctors craft the organ within the body using the patient's own stem cells.\u003cbr/\u003eThe world's first tissue engineered windpipe transplant was in Spain two years ago, but doctors in Iran claim their technique is a first.\u003cbr/\u003eTo this day there's been less than a handful of transplanted windpipes grown from the patient's own stem cells.\u003cbr/\u003eBut the medical advance has spurred on these doctors because the new technology could transform the lives of tens of thousands of patients.\u003cbr/\u003eThis is because Iranian society suffers from a high rate of tracheal and respiratory diseases. \u003cbr/\u003eMuch of it is a legacy of eight year war with Iraq.\u003cbr/\u003eMany people still suffer from health problems caused by mass exposure to chemical weapons following the bombardment. \u003cbr/\u003eThe war ended in 1988, leaving thousands with serious lung injuries. There were 100,000 such casualties.\u003cbr/\u003eAround 52,000 people are still suffering from severe respiratory problems today.\u003cbr/\u003eFor these men and women a new transplant technique has opened up new horizons.\u003cbr/\u003eCar accidents are another major cause of trachea damage in Iran.\u003cbr/\u003eAccording to the Roads and Transportation Ministry 25-thousand people die each year, another 35-thousand are disabled and many of these people could benefit from the transplant.\u003cbr/\u003eThe first person to have the operation here is a 29 year old woman who lost her trachea in a car accident. \u003cbr/\u003eDoctor Jalaladdin Ghanavi, head of the research team says she is in good condition now and can easily breathe.\u003cbr/\u003eDr. Hamid Reza Jabbari, one of the transplant team, says they decided to go ahead with the operation because \"it was impossible for this case to undergo any other treatment such as surgery\". \u003cbr/\u003eJabbari says it was successful and the woman's breathing is now \"completely normal and acceptable.\" \u003cbr/\u003eThe team says nanocapsules containing growth and cellular proteins were injected in to the damaged trachea. \u003cbr/\u003eThree days later the lining of the woman's trachea was injected with a fabricated trachea framework made of natural materials.\u003cbr/\u003eStem cells of the patient's blood then transformed this framework into cartilaginous cells which eventually formed the new trachea. \u003cbr/\u003eBecause the operation involves the patient's own stem cells there is no need for them to take immunosuppressant drugs, which can have many side effects.\u003cbr/\u003eIt takes around 20 to 30 days for the new windpipe to be completed.\u003cbr/\u003eThe operation takes around half an hour and is very cost effective.\u003cbr/\u003eResearch prior to the operation was carried out by Dr. Jalaladdin Ghanavi at the Masih Daneshvari Lung and Tuberculosis Laboratory in northern Tehran, part of the Shahid Beheshti University of Medical Sciences.\u003cbr/\u003eDr. Ghanavi says his driving force has primarily been the \"large number of car crashes that leave many patients in coma with damaged tracheas and most of the time we have to replace some pipes in the tightened parts of trachea\". \u003cbr/\u003eHe says he's also seen a very high number of patients who are ex-soldiers who were injured.\u003cbr/\u003eAccording to Ghanavi when a chemical weapon is blown up near you, the first part of body which is harmed is your eyes. Then skin is damaged and also trachea is next as soon as the injured takes the first breath.\u003cbr/\u003eAli Akbar Velayati, paediatric consultant \u0026amp; chief adviser to Iran's Supreme Leader claims \"this has been done for the first time in the world without any doubt.\" \u003cbr/\u003eGhanavi also argues the operation is a first.\u003cbr/\u003eHe says \"nowhere in the world, a complete functional organ (trachea), that has tissue and a double-structure (has both inner and outer parts of trachea) has been produced yet.\" \u003cbr/\u003eBut other teams in Spain and the UK have transplanted windpipes constructed from their patient's own stem cells.\u003cbr/\u003eThe first was in 2008 on a 30 year old woman who'd suffered tuberculosis.\u003cbr/\u003eThe second patient was a  ten year old British boy.   \u003cbr/\u003eThe clinic in Iran is now holding monitoring the procedure and doctors hope it will soon be widely available to all patients who are in need of 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