{"page":"\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-c03aa079.css\" /\u003e\n\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-517835be.css\" media=\"all\" /\u003e\n\u003cdiv data-title='USA: BALTIMORE: POSSIBLE GENE THERAPY VACCINE FOR CANCER' data-url='/boclips/videos/5c54beaed8eafeecae13d769' data-video-url='/boclips/videos/5c54beaed8eafeecae13d769' id='bo_player_modal'\u003e\n\u003cdiv class='boclips-resource-page modal-dialog panel-container'\u003e\n\u003cdiv class='react-notifications-root'\u003e\u003c/div\u003e\n\u003cdiv class='rp-header'\u003e\n\u003cdiv class='rp-type'\u003e\n\u003ci aria-hidden='true' class='fai fa-regular fa-circle-play'\u003e\u003c/i\u003e\nVideo\n\u003c/div\u003e\n\u003ch1 class='rp-title' id='video-title'\u003e\nUSA: BALTIMORE: POSSIBLE GENE THERAPY VACCINE FOR CANCER\n\u003c/h1\u003e\n\u003cdiv class='rp-actions'\u003e\n\u003cdiv class='mr-1'\u003e\n\u003ca class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"\u003e\u003cspan\u003e\u003cspan\u003eGet Free Access\u003c/span\u003e\u003cspan class=\"\"\u003e for 10 Days\u003c/span\u003e\u003cspan\u003e!\u003c/span\u003e\u003c/span\u003e\u003c/a\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-body'\u003e\n\u003cdiv class='rp-info'\u003e\n\u003cdiv aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'\u003e\u0026times;\u003c/div\u003e\n\u003ci aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003ci aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003cdiv class='rp-rating'\u003e\n\u003cspan class='resource-pool'\u003e\n\u003cspan class='pool-label'\u003ePublisher:\u003c/span\u003e\n\u003cspan class='pool-name'\u003e\n\u003cspan class='text'\u003e\u003ca data-publisher-id=\"30356011\" href=\"/search?publisher_ids%5B%5D=30356011\"\u003eCurated Video\u003c/a\u003e\u003c/span\u003e\n\u003c/span\u003e\n\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-description'\u003e\n\u003cspan class='short-description'\u003eEnglish/NatThere's new hope for men who suffer from prostate cancer -- and it could have implications for how other cancers are treated.Researchers  at Johns Hopkins Oncology Centre in the US- have been working on a gene therapy vaccine...\u003c/span\u003e\n\u003cspan class='full-description hide'\u003eEnglish/Nat\u003cbr/\u003eThere's new hope for men who suffer from prostate cancer -- and it could have implications for how other cancers are treated.\u003cbr/\u003eResearchers  at Johns Hopkins Oncology Centre in the US- have been working on a gene therapy vaccine for the treatment of cancer.\u003cbr/\u003eThey announced on Wednesday they have developed a vaccine that appears to be surprisingly successful in activating the immune system to attack prostatic cancer cells.\u003cbr/\u003eWhether the Yankees win the world series again this year or not, Joe Torre's already a winner.\u003cbr/\u003eHe's a prostate cancer survivor.\u003cbr/\u003eSOUNDBITE:(English)\u003cbr/\u003e\"When you first hear the word cancer you think: a death sentence.  But with all the research that has gone on and all the different treatments that are available now and that will be available in the next six to eight months and in the next years, it's a lot of positive news for the prostate cancer, there is no question about it.\"\u003cbr/\u003eSUPER CAPTION: Joe Torre, manager, New York Yankees\u003cbr/\u003eResearchers tricked the human immune system into recognizing cancerous prostate cells as foreign invaders by genetically engineering the patients' own  cells and injecting them back into the body.\u003cbr/\u003eWriting in the journal Cancer Research, the Johns Hopkins team said they took cancer cells from the patients' own prostate tumours and grew them in a laboratory dish.\u003cbr/\u003eThey then implanted a gene, called GM-CSF into the surgically removed prostate cancer cells.\u003cbr/\u003eThis gene codes for the protein GM-CSF which activates the immune system to recognise tumour cells.\u003cbr/\u003eIn eight cases, researchers were able to grow a culture of the modified, cancerous cells in the laboratory.\u003cbr/\u003eThe cells were then irradiated, which kept them alive but stopped them from multiplying\u003cbr/\u003eany further.\u003cbr/\u003eThe modified cells were then injected back into the patients.\u003cbr/\u003eAfter the vaccine was injected, the immune system of all eight patients produced antibodies to the modified tumour cells, identified as foreign invaders.\u003cbr/\u003eThese antibodies also attacked cancerous prostate cells remaining in the body.\u003cbr/\u003eSOUNDBITE: (English)\u003cbr/\u003e\"We're hopeful this will lead to another generation, a better generation of tumour vaccines for patients with tumours resistant to chemotherapy.\"\u003cbr/\u003eSUPER CAPTION: Jonathan Simons, Johns Hopkins School of Medicine\u003cbr/\u003eWhile it is too early to tell what impact this is going to have on the disease it is a big step in  prostate cancer immunotherapy.\u003cbr/\u003eThe same method could also be applied for the treatment of other cancers.\u003cbr/\u003eSOUNDBITE: (English)\u003cbr/\u003e\"We have focused on prostate cancer, but there are other investigators throughout the country trying to develop vaccines to take on all kinds of cancer, breast cancer, melanoma, colon cancer, kidney cancer.\"\u003cbr/\u003eSUPER CAPTION: William Nelson, Johns Hopkins School of Medicine\u003cbr/\u003eProstate cancer is the second-leading cause of cancer death among men, behind lung cancer.\u003cbr/\u003eXFA        Baltimore, U-S -  Oct. 20, 1999 \u003cbr/\u003e1. Various of lab work\u003cbr/\u003e2. Various of doctors\u003cbr/\u003e3. SOUNDBITE: (English) Joe Torre, manager, New York Yankees\u003cbr/\u003e4. Wide shot Johns Hopkins University\u003cbr/\u003e5. Various of lab work\u003cbr/\u003e6. SOUNDBITE: (English) Jonathan Simons, Johns Hopkins School of Medicine\u003cbr/\u003e7. Various of lab\u003cbr/\u003e8. SOUNDBITE: (English) William Nelson, Johns Hopkins School of Medicine\u003cbr/\u003e9. Various of researchers\u003cbr/\u003e\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='action-container flex justify-between'\u003e\n\u003cbutton aria-expanded='false' aria-label='Read more description' class='rp-full-description' type='button'\u003e\n\u003ci class='fai fa-solid fa-align-left'\u003e\u003c/i\u003e\n\u003cspan id='read_more'\u003eRead More\u003c/span\u003e\n\u003c/button\u003e\n\u003cdiv class='rp-report'\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv aria-labelledby='resource-details-heading' class='rp-info-section'\u003e\n\u003ch2 class='title' id='resource-details-heading'\u003eResource Details\u003c/h2\u003e\n\u003cdiv class='rp-resource-details clearfix'\u003e\n\u003cdiv class='detail'\u003e\n\u003cdl\u003e\n\u003cdt\u003eCurator Rating\u003c/dt\u003e\n\u003cdd\u003e\u003cspan class=\"star-rating\" aria-label=\"3.5 out of 5 stars\" role=\"img\"\u003e\u003ci class=\"fa-solid fa-star text-action\" aria-hidden=\"true\"\u003e\u003c/i\u003e\u003ci 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