{"page":"\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-572d6a42.css\" /\u003e\n\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-f4d0de30.css\" media=\"all\" /\u003e\n\u003cdiv data-title='Scientists experiment with tiny biological machines' data-url='/boclips/videos/5c54bdb0d8eafeecae135eac' data-video-url='/boclips/videos/5c54bdb0d8eafeecae135eac' id='bo_player_modal'\u003e\n\u003cdiv class='boclips-resource-page modal-dialog panel-container'\u003e\n\u003cdiv class='react-notifications-root'\u003e\u003c/div\u003e\n\u003cdiv class='rp-header'\u003e\n\u003cdiv class='rp-type'\u003e\n\u003ci aria-hidden='true' class='fai fa-regular fa-circle-play'\u003e\u003c/i\u003e\nVideo\n\u003c/div\u003e\n\u003ch1 class='rp-title' id='video-title'\u003e\nScientists experiment with tiny biological machines\n\u003c/h1\u003e\n\u003cdiv class='rp-actions'\u003e\n\u003cdiv class='mr-1'\u003e\n\u003ca class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"\u003e\u003cspan\u003e\u003cspan\u003eGet Free Access\u003c/span\u003e\u003cspan class=\"\"\u003e for 10 Days\u003c/span\u003e\u003cspan\u003e!\u003c/span\u003e\u003c/span\u003e\u003c/a\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-body'\u003e\n\u003cdiv class='rp-info'\u003e\n\u003cdiv aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'\u003e\u0026times;\u003c/div\u003e\n\u003ci aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003ci aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003cdiv class='rp-rating'\u003e\n\u003cspan class='resource-pool'\u003e\n\u003cspan class='pool-label'\u003ePublisher:\u003c/span\u003e\n\u003cspan class='pool-name'\u003e\n\u003cspan class='text'\u003e\u003ca data-publisher-id=\"30356011\" href=\"/search?publisher_ids%5B%5D=30356011\"\u003eCurated Video\u003c/a\u003e\u003c/span\u003e\n\u003c/span\u003e\n\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-description'\u003e\n\u003cspan class='short-description'\u003eLos Angeles, California - March 24, 2005 1. Wide shot of laser microscopy lab at the University of California, Los Angeles.     2. Close shot of cell sample being placed in microscope.   3. Close shot of technician looking into...\u003c/span\u003e\n\u003cspan class='full-description hide'\u003eLos Angeles, California - March 24, 2005 \u003cbr/\u003e1. Wide shot of laser microscopy lab at the University of California, Los Angeles.     \u003cbr/\u003e2. Close shot of cell sample being placed in microscope.   \u003cbr/\u003e3. Close shot of technician looking into microscope. \u003cbr/\u003e4. Close shot of hand focussing microscope. \u003cbr/\u003e5. Close microscope image of color coded protein inside cell. \u003cbr/\u003e6. Mid shot of laser array. \u003cbr/\u003e7. Close shot of laser beam. \u003cbr/\u003e8. Close microscope image of glowing quantum dots inside cell as laser is turned on. \u003cbr/\u003e9. Mid shot of Dr. Shimon Weiss in office. \u003cbr/\u003e10. Close sot of Dr. Weiss. \u003cbr/\u003e11. Close computer screen image of quantum dots inside cell. \u003cbr/\u003e12. SOUNDBITE: (English) Dr. Shimon Weiss, UCLA\u003cbr/\u003e13. Mid shot of lab worker testing color coded quantum dots. \u003cbr/\u003e14. Close shot of color coded quantum dots in test tubes illuminated by ultra violet light.  \u003cbr/\u003e15. Close shot of Dr. Anna Wu transferring liquids in lab.  \u003cbr/\u003e16. Close shot of Dr. Wu. \u003cbr/\u003e17. SOUNDBITE: (English) Dr. Anna Wu, UCLA\u003cbr/\u003e18. Wide shot of microscopy lab.\u003cbr/\u003e19. Close shot of cell sample being placed in microscope.\u003cbr/\u003e20. Close onscreen view of cells (green) containing color coded quantum dots\u003cbr/\u003eMedical researchers at the University of California-Los Angeles are pioneering the use of new devices in the emerging field of nanobiotechnology.\u003cbr/\u003eTheir work uses tiny particles that seek out proteins in cancer cells, marking them so they can be identified under a microscope.\u003cbr/\u003eOther applications of nanotechnology could involve using tiny machines to roam the body, delivering therapy at the molecular level.\u003cbr/\u003eThese techniques will aid early diagnosis and treatment of tumours and could change the way cancer is diagnosed and treated. \u003cbr/\u003eResearchers at UCLA's Jonsson Cancer Centre are expecting big things from something really small.\u003cbr/\u003eThe emerging science of nanobiotechnology could hold the key to treating illnesses at the molecular level, using tiny machines visible only under a microscope.\u003cbr/\u003eTheir work borrows from the related field of nanotechnology -- the science of creating very small devices based on the nanometer-length scale.\u003cbr/\u003eA nanometer is one billionth of a meter. \u003cbr/\u003eSome of the earliest applications are in molecular diagnostics. \u003cbr/\u003eUCLA researchers believe nanoparticles, what they refer to as quantum dots, could one day play an important role in cancer diagnosis and treatment. \u003cbr/\u003eDoctor Shimon Weiss at UCLA's Jonsson Cancer Center is already producing quantum dots and using them in animal testing.\u003cbr/\u003eHe says the implications for medicine are revolutionary.\u003cbr/\u003eSOUNDBITE: (English)\u003cbr/\u003e\"We use short peptides, which are little tiny parts of proteins to cover the surface of those little tiny crystals, and also to put zip codes, addresses, that can basically send different colored quantum dots into different parts of the cell tagging individual proteins. And then we use microscopy to look where proteins in the cell are.\"\u003cbr/\u003eSUPER CAPTION: Dr. Shimon Weiss, UCLA\u003cbr/\u003eNanodevices could also sequence single molecules of DNA and  extend the present limits of molecular diagnostics.\u003cbr/\u003eThe pharmaceutical industry is also showing an interest in the new techniques.\u003cbr/\u003eNanotechnology will be applied at all stages of drug development -- from formulations for optimal delivery to diagnostic applications. \u003cbr/\u003eThe most important pharmaceutical applications are in drug delivery. \u003cbr/\u003eSOUNDBITE: (English)\u003cbr/\u003e\"\"I think the other big thing we're working toward with the quantum dots is to be able to look into living organisms. And it's going to be extremely useful in our pre-clinical models. But I think ultimately we'd like to be able to see this working in patients as well, because there you're looking at living tissue in a living person. And it really tells you the biology of the cancer. Whereas once you take the tumor out or once you're just looking at the DNA or the genes in a cell, the cell is dead.\"\u003cbr/\u003eSUPER CAPTION: Dr. Anna Wu, UCLA\u003cbr/\u003eNanobiotechnology could allow pharmaceutical drugs to be delivered directly to diseased cells. \u003cbr/\u003eThese tiny machines would roam the body, supplying drugs autonomously, effectively doing the job of diagnosis and treatment themselves, in some cases removing the need for surgery.\u003cbr/\u003eResearchers say nanotechnology could also improve implants and tissue engineering as well.\u003cbr/\u003eAt this early stage, little is known about the possible side effects of releasing nanobots into the human body.\u003cbr/\u003eResearch is underway to address these issues. \u003cbr/\u003eAs yet, nanobiotechnology is largely unregulated, but the debate is set to hot up as products reach the stage where they are ready to enter the market.\u003cbr/\u003e\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv 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