{"page":"\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-c03aa079.css\" /\u003e\n\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-517835be.css\" media=\"all\" /\u003e\n\u003cdiv data-title='Flu virus put into noses of volunteers willing to sneeze for science' data-url='/boclips/videos/5c54bd3bd8eafeecae132936' data-video-url='/boclips/videos/5c54bd3bd8eafeecae132936' id='bo_player_modal'\u003e\n\u003cdiv class='boclips-resource-page modal-dialog panel-container'\u003e\n\u003cdiv class='react-notifications-root'\u003e\u003c/div\u003e\n\u003cdiv class='rp-header'\u003e\n\u003cdiv class='rp-type'\u003e\n\u003ci aria-hidden='true' class='fai fa-regular fa-circle-play'\u003e\u003c/i\u003e\nVideo\n\u003c/div\u003e\n\u003ch1 class='rp-title' id='video-title'\u003e\nFlu virus put into noses of volunteers willing to sneeze for science\n\u003c/h1\u003e\n\u003cdiv class='rp-actions'\u003e\n\u003cdiv class='mr-1'\u003e\n\u003ca class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"\u003e\u003cspan\u003e\u003cspan\u003eGet Free Access\u003c/span\u003e\u003cspan class=\"\"\u003e for 10 Days\u003c/span\u003e\u003cspan\u003e!\u003c/span\u003e\u003c/span\u003e\u003c/a\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-body'\u003e\n\u003cdiv class='rp-info'\u003e\n\u003cdiv aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'\u003e\u0026times;\u003c/div\u003e\n\u003ci aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003ci aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003cdiv class='rp-rating'\u003e\n\u003cspan class='resource-pool'\u003e\n\u003cspan class='pool-label'\u003ePublisher:\u003c/span\u003e\n\u003cspan class='pool-name'\u003e\n\u003cspan class='text'\u003e\u003ca data-publisher-id=\"30356011\" href=\"/search?publisher_ids%5B%5D=30356011\"\u003eCurated Video\u003c/a\u003e\u003c/span\u003e\n\u003c/span\u003e\n\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-description'\u003e\n\u003cspan class='short-description'\u003eAP TelevisionBethesda, Maryland - January 14, 20141. Flu study participant laying down on hospital bed as doctor and assistants stand over him2. Tight of doctor administering flu virus through volunteer's nose, pull out to wide3. Tight...\u003c/span\u003e\n\u003cspan class='full-description hide'\u003eAP Television\u003cbr/\u003eBethesda, Maryland - January 14, 2014\u003cbr/\u003e1. Flu study participant laying down on hospital bed as doctor and assistants stand over him\u003cbr/\u003e2. Tight of doctor administering flu virus through volunteer's nose, pull out to wide\u003cbr/\u003e3. Tight of doctor administering flu virus in volunteer's second nostril\u003cbr/\u003e4. SOUNDBITE: (English) Daniel Bennett, Flu study volunteer:\u003cbr/\u003e\"From what my understanding is I think it's a lower strand of the flu that they're testing right now. I have absolutely no clue, and I'm prepared for the worst.\"\u003cbr/\u003e5. Wide of Bennett taking a book from hospital nightstand\u003cbr/\u003e6. Tight of book\u003cbr/\u003e7. Mid of Bennett reading in hospital bed\u003cbr/\u003e8. SOUNDBITE: (English) Dr. Matthew Memoli, Laboratory of Infectious Diseases, National Institutes of Health (NIH):\u003cbr/\u003e\"We're taking healthy volunteers and we're administering a flu virus to them.  So it's very important that what we're inducing is not something that would be unsafe or really that unpleasant for our volunteers.\"\u003cbr/\u003e9. Wide of isolation unit hallway and common area as seen through window\u003cbr/\u003e10. Bennett eating yogurt in the common area of the isolation unit\u003cbr/\u003e11. Tight of Bennett using video game controller\u003cbr/\u003e12. Bennett playing video game\u003cbr/\u003e13. SOUNDBITE: (English) Daniel Bennett, Flu study volunteer:\u003cbr/\u003e\"We started 'Band of Brothers' yesterday. Several of us have not seen 'The Godfather' series, so that's on the list.  We have full access to the DVD library.\"\u003cbr/\u003e14. Tight of sign on doorway leading into isolation/quarantine unit reading, \"This unit is on respiratory isolation.  Please put on a mask and gloves before entering.\"\u003cbr/\u003e15. Wide of hallway in isolation unit\u003cbr/\u003e16. Mid of hand sanitiser in unit\u003cbr/\u003e17. Pan down plastic gloves in unit\u003cbr/\u003e18. Pan from isolation until door to Bennett sitting in kitchen, as seen through windows into unit\u003cbr/\u003e19. Memoli talking to reporter in hallway just outside unit\u003cbr/\u003e20. SOUNDBITE: (English) Dr. Matthew Memoli, Laboratory of Infectious Diseases, NIH:\u003cbr/\u003e\"We've had a number of pandemics occur throughout history. Interestingly, despite all the work we've done and the studying of the virus and of the infections, there are still many questions that are unanswered and things that we need to investigate further.\"\u003cbr/\u003eAP Television FILE\u003cbr/\u003eUndated  \u003cbr/\u003e21. Various of a doctor checking a patient\u003cbr/\u003e22. Various of a nurse filling a vial with flu vaccine\u003cbr/\u003e23. Various of a woman getting the flu vaccine shot\u003cbr/\u003eAP Television \u003cbr/\u003eBethesda, Maryland - January 14, 2014\u003cbr/\u003e24. SOUNDBITE: (English) Dr. Matthew Memoli, Laboratory of Infectious Diseases, NIH:\u003cbr/\u003e\"We can look at people, their immune system and the flu and understand those interactions so that hopefully we can learn new information that could help us improve vaccines in the future. The other thing we can do with a study like this is we can use this model to help us evaluate new drugs and new vaccines in the future in a rapid and efficient manner with a small number of patients.\"\u003cbr/\u003eAP Television \u003cbr/\u003eBethesda, Maryland - January 21, 2014\u003cbr/\u003e25. Various of Memoli asking questions of and examining Bennett on day eight of the flu isolation study\u003cbr/\u003e26. SOUNDBITE:  (English) Daniel Bennett, Flu study volunteer:\u003cbr/\u003e\"I felt fine most of the time. I experienced a little head congestion, sinus pressure, slight achiness and slight chills, just general weariness.\"\u003cbr/\u003e27. Wide of Bennett sitting at common room table as he nears the end of his time in isolation\u003cbr/\u003e28. SOUNDBITE:  (English) Daniel Bennett, Flu study volunteer:\u003cbr/\u003e\"It kind of felt like you were on a cruise ship for parts of it.  We're in quarantine, so we have a window that looks out onto the courtyard.  I didn't really look at it much, and other than that you're just seeing the interior of the hallway and this common room area for, what, eight days straight.\"\u003cbr/\u003eAP Television \u003cbr/\u003eBethesda, Maryland - January 14, 2014\u003cbr/\u003e29. Pan from hallway to Bennett room and bed\u003cbr/\u003e30. SOUNDBITE:  (English) Daniel Bennett, Flu study volunteer:\u003cbr/\u003e\"I received a very scolding email from my mother that night before I went in that started by saying, 'Dear Danny, I honestly, I know your study starts tomorrow. I honestly can't say I'm happy that you're doing it because you know that I'm not, but it's your body, and if you're going to sell it to science, that's you're prerogative.'\"\u003cbr/\u003e31. Tight of Bennett reading in common room kitchen\u003cbr/\u003e32. Bennett in kitchen as seen through windows looking into isolation unit\u003cbr/\u003eGovernment scientists in the U.S are deliberately giving people flu by squirting the live virus straight up their noses.\u003cbr/\u003eIt's part of a research project that aims to improve flu vaccines.\u003cbr/\u003eDanny Bennett, a 26-year-old restaurant worker from College Park, Maryland has agreed to get sick for science. \u003cbr/\u003eHe's having the flu virus squirted up his nostrils as part of a study by the U.S National Institutes of Health (NIH) that aims to improve flu vaccines. \u003cbr/\u003eThe incentive is $3,000 to compensate for his time.\u003cbr/\u003e\"I'm prepared for the worst,\" says Bennett. \u003cbr/\u003eDr. Matthew Memoli is leading the study at the NIH Hospital in Bethesda that aims to infect up to 100 adults over the next year.\u003cbr/\u003eHe says: \"We're taking healthy volunteers and we're administering a flu virus to them.  So it's very important that what we're inducing is not something that would be unsafe or really that unpleasant for our volunteers.\"\u003cbr/\u003eFlu is widespread at this time of year, so why not just study people that are already sick? According to Memoli. that wouldn't let scientists measure how the immune system reacts through each step of infection, starting with that first exposure to the virus. \u003cbr/\u003eThis isn't an experiment to be taken lightly - flu can be fatal. For safety, Memoli has chosen a dose that produces mild to moderate symptoms, and he accepts only volunteers who are healthy and no older than 50.\u003cbr/\u003eTo avoid spreading the germs, participants must spend at least nine days quarantined inside a special isolation ward being closely monitored. They're not released until nasal tests prove they're no longer contagious.\u003cbr/\u003eFortunately Bennett and the other volunteers here have full access to the hospital DVD library. \u003cbr/\u003eBennett says: \"We started 'Band of Brothers' yesterday. Several of us have not seen 'The Godfather' series, so that's on the list.  We have full access to the DVD library.\" \u003cbr/\u003eThe best defence against influenza is a yearly vaccine, but it's far from perfect. The vaccine is least effective in people age 65 and older - the group most susceptible to flu. This is probably because the immune system weakens with age.\u003cbr/\u003eUnderstanding how younger adult bodies fight flu may help scientists determine what the more vulnerable elderly are missing and help develop more protective vaccines for everyone.\u003cbr/\u003eMemoli says: \"We've had a number of pandemics occur throughout history. Interestingly, despite all the work we've done and the studying of the virus and of the infections, there are still many questions that are unanswered and things that we need to investigate further.\"\u003cbr/\u003eThe flu vaccine is designed to raise people's levels of a particular flu-fighting antibody. It targets a protein that acts like the virus' coat, called hemagglutinin. This is the \"H\" in H1N1, the strain that caused the 2009 pandemic. But it's not clear what antibody level is best to aim for - or whether a certain amount means you're protected against getting sick at all, or that you'd get a mild case instead of a severe one.\u003cbr/\u003eMemoli is infecting two groups - people with low antibody levels and those with high levels. Some were recently vaccinated, and some weren't. He'll compare how sick they get, how long they're contagious for and how their immune systems react. \u003cbr/\u003e\"The other thing we can do with a study like this is we can use this model to help us evaluate new drugs and new vaccines in the future in a rapid and efficient manner with a small number of patients,\" says Memoli.  \u003cbr/\u003eA few days after being given the virus, Bennett had A runny nose and felt achy - symptoms of mild flu.\u003cbr/\u003eSo far, Memoli's patients are becoming contagious a day or two before they start feeling bad, one reason flu spreads so easily. \u003cbr/\u003eHe sees a range of symptoms, from sniffles to a few days of moderate fever, fatigue and congestion.\u003cbr/\u003eBy day eight of his isolation, Bennett's case of the flu was on its way out.\u003cbr/\u003eHe says: \"I felt fine most of the time.  I experienced a little head congestion, sinus pressure, slight achiness and slight chills, just general weariness.\"\u003cbr/\u003eHe says it was easy to lose track of time while under quarantine:\u003cbr/\u003e\"It kind of felt like you were on a cruise ship for parts of it. You're just seeing the interior of the hallway and this common room area for, what, eight days straight.\"\u003cbr/\u003eBennett says overall he had a good experience, felt safe throughout and liked getting a first-hand look at how scientific research is done.\u003cbr/\u003eHis mother, on the other hand, was never keen on the idea.\u003cbr/\u003e\"I received a very scolding email from my mother that night before I went in. It said,\"'I honestly can't say I'm happy that you're doing it because you know that I'm not, but it's your body, and if you're going to sell it to science, that's you're prerogative,'\" says Bennett. \u003cbr/\u003eClients are reminded: \u003cbr/\u003e(i) to check the terms of their licence agreements for use of content outside news programming and that further advice and assistance can be obtained from the AP Archive on: Tel +44 (0) 20 7482 7482 Email: info@aparchive.com. \u003cbr/\u003e(ii) they should check with the applicable collecting society in their Territory regarding the clearance of any sound recording or performance included within the AP Television News service \u003cbr/\u003e(iii) they have editorial responsibility for the use of all and any content included within the AP Television News service and for libel, privacy, compliance and third party rights applicable to their Territory.\u003cbr/\u003e\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='action-container flex 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