Sickle Cell Anemia Teacher Resources
Find Sickle Cell Anemia lesson plans and worksheets
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Howard Hughes Medical Institute
Sickle Cell Anemia
The most common blood disorder in the United States, sickle cell impacts more than 70,000 Americans. Understanding the genetic coding that leads to this disease might one day help scientists prevent it altogether. Using a promising...
Towson University
Mystery of the Crooked Cell
Can your class solve the Mystery of the Crooked Cell? Junior geneticists collaborate to learn about sickle cell anemia in a fascinating lesson plan. The included materials help them to examine the genetic factors behind the disease...
Curated OER
Mutations
After studying DNA replication and the genetics of inheritance, this slide show is useful for explaining specific mutations that can happen and result in an illness. Sickle cell anemia, and cystic fibrosis are explained on a genetic...
Towson University
Mystery Disease
How did scientists determine the cause of illness before technology? Science scholars play the role of medical researcher in an engaging guided inquiry activity. Using observations, technical reading, and Punnett squares, learners...
Serendip
Genetics
A handout on genetic inheritance begins with a reading on alleles and how they can result in albinism. Junior geneticists learn to complete Punnett squares and participate in a coin toss simulation of allele pairing. They also learn...
Curated OER
Human Genetic Diseases
Although there are a few missing titles in this collection of slides, if your class has prior knowledge of genetic diseases then this resource could be useful. The mechanism of genetic inheritance are covered and both flow charts and...
Curated OER
Human Genetic Diseases
Although there are a few missing titles in this collection of slides, if your class has the support of a genetic disease lecture to accompany it, this resource will be very useful. The mechanism of genetic inheritance is covered. Flow...
TED-Ed
How This Disease Changes the Shape of Your Cells
Just what exactly is sickle cell disease? A short, animated video explains how the cell adaption works, how inheriting the sickle cell trait can be an advantage in malaria-prone areas, and how sickle cell disease can be deadly.
Curated OER
Hereditary Defects: Down Syndrome and Sickle Cell Anemia
Students solve problems like the following examples: 1. If you have 10,000 women, age 30, who have babies and one in 900 of these births will result in a Down syndrome baby, how many will have this disease? 2. 5,000 babies are born;...
Curated OER
Mutations
The basics of mutation types and some potential effects of those are described and diagrammed here. Each detail is very clear and includes the labels and translation change exhibited. A great slideshow to expand on DNA replication issues.
Curated OER
Raven Chapter 13 Guided Notes: Patterns of Inheritance
In this short space, it would be impossible to describe the breadth of this seven-page genetics worksheet. Geared toward AP or college biology learners, they explore not only the basic vocabulary and concepts, but also the Law of...
Howard Hughes Medical Institute
Testing a Hypothesis
Are sickle cell disease and malaria related somehow? Scholars learn about both illnesses and the hypotheses that they are related. They discuss, view a video, and answer questions to demonstrate understanding. The resource includes an...
Serendip
From Gene to Protein - Transcription and Translation
Learners identify the different steps involved in DNA transcription. In this genetics lesson, pupils complete a worksheet and model the translation process with a paper chain activity. They watch a video on sickle cell anemia and explain...
Curated OER
Allele Frequencies and Sickle Cell Anemia Lab
Students investigate how selective forces like food, predation and diseases affect evolution. In this genetics lesson, students use red and white beans to simulate the effect of malaria on allele frequencies. They analyze data collected...
Kenan Fellows
Unit 3: Genetic Variation
What happens when genes change? Junior genetic investigators examine the effects of mutation in the third unit of a four-part Biotechnology series. Individuals discover the types of mutations through a series of PowerPoints, then partner...
Serendip
From Gene to Protein via Transcription and Translation
DNA carries the codes for creating just the right protein. A well-designed lesson plan leads pupils through the process from start to finish and everywhere in between. Guiding questions with supporting video help scholars understand the...
Howard Hughes Medical Institute
Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics
People with the sickle cell trait, but not sickle cell disease, find natural protection against malaria. Scholars consider various combinations of genotypes and environmental factors to determine if children might have sickle cell...
FuseSchool
Mutations and Natural Selection
Mutations have a bad reputation ... but are they always harmful? Junior geneticists explore mutations and their effects in a Fuse School Evolution video. The content features sickle cell disease, its effects on the body, and its ability...
Curated OER
Solving Crosses
Genetics hopefuls solve Punnett Squares for monohybrid and dihybrid crosses. An example of each is provided to teach the process. Other heredity patterns are mentioned and genetic disorders are listed in the second half of the...
Howard Hughes Medical Institute
How Do Fibers Form?
The proteins inside a cell determine the shape of the cell. While most red blood cells have a circular shape, those with sickle cell take the shape of a sickle. This change in shape causes multiple issues in the system. Scholars solve...
Curated OER
The Electrophoresis of Human Hemoglobin
High schoolers are presented with a scenario that requires them to electrophoreses human hemoglobin samples in order to confirm a diagnosis of sickle cell anemia and/or to determine whether individuals in the scenario are carriers of the...
America's Blood Centers
My Blood, Your Blood
Dracula isn't the only one who needs blood to survive. The eight-part unit includes seven lessons, five demonstrations, seven labs, and a project to organize a blood drive. Class members learn about the parts of...
Amoeba Sisters
Mutations: The Potential Power of a Small Change
Are the only mutants you know Ninja Turtles or X-Men? The video explains both gene mutation and chromosome mutation. It includes the subtypes of mutations for each major type, the times when mutations are more likely to happen, and...
Give and Let Live
Blood and Transplant: Blood
Why is blood donation so important, anyway? Science and health classes across multiple grades benefit from an in-depth look into the need for and process of blood donation. With an emphasis on presenting the topic in a non-threatening...